After your COVID-19 vaccination

What to expect after your vaccination.

Common side effects

As with any vaccine, you may have some temporary side effects after receiving a COVID-19 vaccine. Common side effects after AstraZeneca COVID-19 vaccine include:

  • injection site pain or tenderness
  • tiredness
  • headache
  • muscle pain
  • fever and chills

Most side effects are mild and temporary, going away within 1-2 days. As with any medicine or vaccine, there may be rare and/or unknown side effects.

Rare side effects

Rare side effects that have been reported after the AstraZeneca COVID-19 vaccination are:

Severe allergic reaction (anaphylaxis)

You should seek medical attention after vaccination if you think you are having an allergic reaction. Call 000 if you experience severe symptoms, such as difficulty breathing, wheezing, a fast heartbeat or collapsing.

Thrombosis with thrombocytopenia syndrome

Thrombosis with thrombocytopenia syndrome (TTS) is rare and occurs around 4-26 days after vaccination. Symptoms can include abdominal pain and/or severe headache that does not settle with pain relief. People should seek medical attention immediately if they experience these symptoms:

  • a severe persistent headache with additional features:
    • appears at least 4 days after vaccination
    • does not improve with simple painkillers
    • may be worse when lying down or accompanied by nausea and vomiting
  • neurological symptoms such as:
    • blurred vision
    • difficulty with speech
    • drowsiness
    • seizures
  • shortness of breath or chest pain
  • a swollen leg
  • persistent abdominal (belly) pain
  • tiny blood spots under the skin away from the site of injection together with symptoms above.

Be sure to tell your doctor or healthcare provider that you have recently received the vaccine.

For symptoms which are not urgent, you can see your regular healthcare provider (usually your GP).

Reporting side effects

Your health care professional (GP) or vaccination provider can report suspected side effects on your behalf.

It is possible to self-report any adverse events to SAEFVIC via:

It is important to remember that serious side effects are very rare and for people 50 years and over, the Australian Technical Advisory Group on Immunisation (ATAGI) continues to advise that the benefit of vaccination with AstraZeneca COVID vaccine outweighs the risks associated with vaccination.

Remember your second appointment

Two doses of the AstraZeneca COVID-19 vaccine are required to give the best protection. These can be safely administered 4-12 weeks apart (12 weeks is the recommended gap).

The second dose is likely to prolong the duration of protection against COVID-19.  

At the end of your first appointment, the team will work with you to book your second dose of the vaccine. If you need to reschedule or cancel, please call 1800 675 398.

To continue to keep yourself and others protected, remember to continue your COVID-safe habits such as maintaining physical distance, hand washing or sanitising, checking in at public places and wearing a mask when required to do so, even after vaccination.

How the information you provide at your appointment is used

For information on how your personal details are collected, stored and used visit

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